Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-AP-4 complex subunit beta-1 (595-645 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
AP4B1 |
Gene ID: |
10717 |
Uniprot ID: |
AP4B1_HUMAN |
Immunogen Region: |
595-645 aa |
Specificity: |
This antibody detects endogenous levels of AP4B1 at Human/Mouse |
Immunogen: |
Synthesized peptide derived from the human AP4B1 at the amino acid range 595-645 |
Function | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (Probable). |
Protein Name | Ap-4 Complex Subunit Beta-1Ap-4 Adaptor Complex Subunit BetaAdaptor-Related Protein Complex 4 Subunit Beta-1Beta Subunit Of Ap-4Beta4-Adaptin |
Database Links | Reactome: R-HSA-432720Reactome: R-HSA-432722 |
Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane Protein |
Alternative Antibody Names | Anti-Ap-4 Complex Subunit Beta-1 antibodyAnti-Ap-4 Adaptor Complex Subunit Beta antibodyAnti-Adaptor-Related Protein Complex 4 Subunit Beta-1 antibodyAnti-Beta Subunit Of Ap-4 antibodyAnti-Beta4-Adaptin antibodyAnti-AP4B1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance