• Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-AP4B1 antibody (595-645 aa) (STJ195839)

SKU:
STJ195839

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AP-4 complex subunit beta-1 (595-645 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AP4B1
Gene ID: 10717
Uniprot ID: AP4B1_HUMAN
Immunogen Region: 595-645 aa
Specificity: This antibody detects endogenous levels of AP4B1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human AP4B1 at the amino acid range 595-645
Function Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (Probable).
Protein Name Ap-4 Complex Subunit Beta-1
Ap-4 Adaptor Complex Subunit Beta
Adaptor-Related Protein Complex 4 Subunit Beta-1
Beta Subunit Of Ap-4
Beta4-Adaptin
Database Links Reactome: R-HSA-432720
Reactome: R-HSA-432722
Cellular Localisation Golgi Apparatus
Trans-Golgi Network Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Ap-4 Complex Subunit Beta-1 antibody
Anti-Ap-4 Adaptor Complex Subunit Beta antibody
Anti-Adaptor-Related Protein Complex 4 Subunit Beta-1 antibody
Anti-Beta Subunit Of Ap-4 antibody
Anti-Beta4-Adaptin antibody
Anti-AP4B1 antibody

Information sourced from Uniprot.org

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