Tissue Specificity | Present in all adult tissues examined. |
Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
Protein Name | Ap-3 Complex Subunit Sigma-2Ap-3 Complex Subunit Sigma-3bAdaptor-Related Protein Complex 3 Subunit Sigma-2Sigma-3b-AdaptinSigma3b-AdaptinSigma-Adaptin 3b |
Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
Alternative Antibody Names | Anti-Ap-3 Complex Subunit Sigma-2 antibodyAnti-Ap-3 Complex Subunit Sigma-3b antibodyAnti-Adaptor-Related Protein Complex 3 Subunit Sigma-2 antibodyAnti-Sigma-3b-Adaptin antibodyAnti-Sigma3b-Adaptin antibodyAnti-Sigma-Adaptin 3b antibodyAnti-AP3S2 antibody |
Information sourced from Uniprot.org