| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AP3D1 (520-700) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AP3D1 |
| Gene ID: |
8943 |
| Uniprot ID: |
AP3D1_HUMAN |
| Immunogen Region: |
520-700 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 520-700 of human AP3D1 (NP_003929.4). |
| Immunogen Sequence: |
AVYVQNVVKLYASILQQKEQ AGEAEGAQAVTQLMVDRLPQ FVQSADLEVQERASCILQLV KHIQKLQAKDVPVAEEVSAL FAGELNPVAPKAQKKVPVPE GLDLDAWINEPLSDSESEDE RPRAVFHEEEQRRPKHRPSE ADEEELARRREARKQEQANN PFYIKSSPSPQKRYQDTPGV E |
| Tissue Specificity | Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis. |
| Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Protein Name | Ap-3 Complex Subunit Delta-1Ap-3 Complex Subunit DeltaAdaptor-Related Protein Complex 3 Subunit Delta-1Delta-Adaptin |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Ap-3 Complex Subunit Delta-1 antibodyAnti-Ap-3 Complex Subunit Delta antibodyAnti-Adaptor-Related Protein Complex 3 Subunit Delta-1 antibodyAnti-Delta-Adaptin antibodyAnti-AP3D1 antibodyAnti-PRO0039 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
