Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-AP-1 complex subunit gamma-1 is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
AP1G1 |
Gene ID: |
164 |
Uniprot ID: |
AP1G1_HUMAN |
Specificity: |
AP1G1 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from part of the human protein |
Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes. |
Protein Name | Ap-1 Complex Subunit Gamma-1Adaptor Protein Complex Ap-1 Subunit Gamma-1Adaptor-Related Protein Complex 1 Subunit Gamma-1Clathrin Assembly Protein Complex 1 Gamma-1 Large ChainGamma1-AdaptinGolgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 |
Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
Cellular Localisation | Golgi ApparatusCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmPerinuclear RegionClathrin-Coated VesicleMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi ComplexCo-Localizes With Aftph/Aftiphilin In The Cytoplasm |
Alternative Antibody Names | Anti-Ap-1 Complex Subunit Gamma-1 antibodyAnti-Adaptor Protein Complex Ap-1 Subunit Gamma-1 antibodyAnti-Adaptor-Related Protein Complex 1 Subunit Gamma-1 antibodyAnti-Clathrin Assembly Protein Complex 1 Gamma-1 Large Chain antibodyAnti-Gamma1-Adaptin antibodyAnti-Golgi Adaptor Ha1/Ap1 Adaptin Subunit Gamma-1 antibodyAnti-AP1G1 antibodyAnti-ADTG antibodyAnti-CLAPG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance