Anti-ANXA13 antibody (STJ192278)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
STJ192278
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General Information

Short DescriptionRabbit polyclonal anti-Annexin A13 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolANXA13
Gene ID312
Uniprot IDANX13_HUMAN
ImmunogenSynthesized peptide derived from part of the human protein
SpecificityANX13 Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Function Isoform A: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup. Isoform B: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner, but requires higher calcium levels for membrane binding than isoform A. Half-maximal membrane binding requires about 320 uM calcium.
Protein Name Annexin A13
Annexin Xiii
Annexin-13
Intestine-Specific Annexin
Isa
Database Links
Cellular Localisation Apical Cell Membrane
Cell Membrane
Lipid-Anchor
Cytoplasmic Vesicle
Myristoylation Anchors The Protein To The Membrane
But The Protein Also Displays Calcium-Dependent
Reversible Binding To Lipid Membranes
Associated With The Plasma Membrane Of Undifferentiated
Proliferating Crypt Epithelial Cells As Well As Differentiated Villus Enterocytes
Alternative Antibody Names Anti-Annexin A13 antibody
Anti-Annexin Xiii antibody
Anti-Annexin-13 antibody
Anti-Intestine-Specific Annexin antibody
Anti-Isa antibody
Anti-ANXA13 antibody
Anti-ANX13 antibody

Information sourced from Uniprot.org

Citations

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