Anti-AMN antibody (STJ192224)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Protein amnionless for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AMN |
| Gene ID | 81693 |
| Uniprot ID | AMNLS_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | AMNLS Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. A soluble form arises by proteolytic removal of the membrane anchor. |
| Function | Membrane-bound component of the endocytic receptor formed by AMN and CUBN. Required for normal CUBN glycosylation and trafficking to the cell surface. The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12. Required for normal CUBN-mediated protein transport in the kidney (Probable). |
| Protein Name | Protein Amnionless Cleaved Into - Soluble Protein Amnionless |
| Database Links | Reactome: R-HSA-3359462Reactome: R-HSA-3359463Reactome: R-HSA-8964011Reactome: R-HSA-9758881 |
| Cellular Localisation | Isoform 1: Apical Cell MembraneSingle-Pass Type I Membrane ProteinCell MembraneEndosome MembraneMembraneCoated PitSoluble Protein Amnionless: Secreted |
| Alternative Antibody Names | Anti-Protein Amnionless Cleaved Into - Soluble Protein Amnionless antibodyAnti-AMN antibodyAnti-UNQ513 antibodyAnti-PRO1028 antibody |
Information sourced from Uniprot.org