• STJ70323 (1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • HEK293 overexpressing ILPIP (RC203432) and probed with STJ70323 (mock transfection in first lane) , tested by Origene.
  • STJ70323 Immunofluorescence analysis of paraformaldehyde fixed U251 cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing nuclear and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).

Anti-ALS2CR2/ILPIP antibody (C-Term) (STJ70323)

SKU:
STJ70323-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC/IF
Reactivity: Human/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ALS2CR2/ILPIP (C-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-3-5µg/ml
IF-Strong expression of the protein seen in the nuclei and cytoplasm of U251 cells. 10µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: STRADB
Gene ID: 55437
Uniprot ID: STRAB_HUMAN
Immunogen Region: C-Term
Accession Number: NP_061041.2; AAF71042.1
Specificity: This is expected to recognise both human isoforms: ILPIP-alpha (NP_061041.2) and ILPIP-beta (AAF71042.1).
Immunogen Sequence: CDFPDEKDSYWEF
Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Protein Name Ste20-Related Kinase Adapter Protein Beta
Strad Beta
Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 2 Protein
Cals-21
Ilp-Interacting Protein
Pseudokinase Als2cr2
Database Links Reactome: R-HSA-380972
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Ste20-Related Kinase Adapter Protein Beta antibody
Anti-Strad Beta antibody
Anti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 2 Protein antibody
Anti-Cals-21 antibody
Anti-Ilp-Interacting Protein antibody
Anti-Pseudokinase Als2cr2 antibody
Anti-STRADB antibody
Anti-ALS2CR2 antibody
Anti-ILPIP antibody
Anti-PRO1038 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance