| Short Description : | Rabbit polyclonal anti-Centrosome-associated protein ALMS1 (1530-1610 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALMS1 |
| Gene ID: | 7840 |
| Uniprot ID: | ALMS1_HUMAN |
| Immunogen: | Synthesized peptide derived from ALMS1 at the amino acid range 1530-1610 |
| Immunogen Region: | 1530-1610 aa |
| Specificity: | ALMS1 Polyclonal Antibody detects endogenous levels of ALMS1 protein. |
| Function | Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells. |
| Protein Name | Centrosome-Associated Protein Alms1Alstrom Syndrome Protein 1 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal BodySpindle PoleAssociated With Centrosomes And Basal Bodies At The Base Of Primary CiliaSpecifically Locates To The Proximal Ends Of Centrioles And Basal BodiesColocalizes Partially With Ncapd2 At These SitesDuring Mitosis Localizes To Both Spindle Poles |
| Alternative Antibody Names | Anti-Centrosome-Associated Protein Alms1 antibodyAnti-Alstrom Syndrome Protein 1 antibodyAnti-ALMS1 antibodyAnti-KIAA0328 antibody |
Information sourced from Uniprot.org
