Anti-ALDH7A1 antibody (430-539) (STJ111351)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ALDH7A1 (430-539) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALDH7A1 |
| Gene ID | 501 |
| Uniprot ID | AL7A1_HUMAN |
| Immunogen Region | 430-539 |
| Immunogen Sequence | APILYVFKFKNEEEVFAWNN EVKQGLSSSIFTKDLGRIFR WLGPKGSDCGIVNVNIPTSG AEIGGAFGGEKHTGGGRESG SDAWKQYMRRSTCTINYSKD LPLAQGIKFQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 430-539 of human ALDH7A1 (NP_001173.2). |
Additional Info
| Tissue Specificity | Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue. |
| Function | Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. |
| Protein Name | Alpha-Aminoadipic Semialdehyde DehydrogenaseAlpha-Aasa DehydrogenaseAldehyde Dehydrogenase Family 7 Member A1Antiquitin-1Betaine Aldehyde DehydrogenaseDelta1-Piperideine-6-Carboxylate DehydrogenaseP6c Dehydrogenase |
| Database Links | Reactome: R-HSA-6798163Reactome: R-HSA-71064 |
| Cellular Localisation | Isoform 2: CytoplasmCytosolNucleusIsoform 1: Mitochondrion |
| Alternative Antibody Names | Anti-Alpha-Aminoadipic Semialdehyde Dehydrogenase antibodyAnti-Alpha-Aasa Dehydrogenase antibodyAnti-Aldehyde Dehydrogenase Family 7 Member A1 antibodyAnti-Antiquitin-1 antibodyAnti-Betaine Aldehyde Dehydrogenase antibodyAnti-Delta1-Piperideine-6-Carboxylate Dehydrogenase antibodyAnti-P6c Dehydrogenase antibodyAnti-ALDH7A1 antibodyAnti-ATQ1 antibody |
Information sourced from Uniprot.org