| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AIP |
| Gene ID: | 9049 |
| Uniprot ID: | AIP_HUMAN |
| Immunogen Region: | 1-330 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human AIP (NP_003968.3). |
| Immunogen Sequence: | MADIIARLREDGIQKRVIQE GRGELPDFQDGTKATFHYRT LHSDDEGTVLDDSRARGKPM ELIIGKKFKLPVWETIVCTM REGEIAQFLCDIKHVVLYPL VAKSLRNIAVGKDPLEGQRH CCGVAQMREHSSLGHADLDA LQQNPQPLIFHMEMLKVESP GTYQQDPWAMTDEEKAKAVP LIHQEGNRLYREGHVKEAAA KYYDAIACLKNLQMKEQPGS PEWIQLDQQITPLLLNYCQ |
| Tissue Specificity | Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver. |
| Function | May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. Cellular negative regulator of the hepatitis B virus (HBV) X protein. |
| Protein Name | Ah Receptor-Interacting ProteinAipAryl-Hydrocarbon Receptor-Interacting ProteinHbv X-Associated Protein 2Xap-2Immunophilin Homolog Ara9 |
| Database Links | Reactome: R-HSA-8937144Reactome: R-HSA-8950505 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ah Receptor-Interacting Protein antibodyAnti-Aip antibodyAnti-Aryl-Hydrocarbon Receptor-Interacting Protein antibodyAnti-Hbv X-Associated Protein 2 antibodyAnti-Xap-2 antibodyAnti-Immunophilin Homolog Ara9 antibodyAnti-AIP antibodyAnti-XAP2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and AIP knockout (KO) HeLa cells, using [KO Validated] AIP Rabbit polyclonal antibody (STJ11100845) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89779/358250/STJ11100845_1__57247.1713122586.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and AIP knockout (KO) HeLa cells, using [KO Validated] AIP Rabbit polyclonal antibody (STJ11100845) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
