Anti-AIMP2 antibody (STJA0006812)

SKU:
STJA0006812
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AIMP2
Gene ID: 7965
Uniprot ID: AIMP2_HUMAN
Specificity: This antibody detects endogenous levels of JTV1 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human JTV1
Function Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Protein Name Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 2
Multisynthase Complex Auxiliary Component P38
Protein Jtv-1
Database Links Reactome: R-HSA-2408522
Reactome: R-HSA-379716
Reactome: R-HSA-9856649
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Following Dna Damage
Dissociates From The Aminoacyl-Trna Synthase Complex And Translocates From The Cytoplasm To The Nucleus
Alternative Antibody Names Anti-Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 2 antibody
Anti-Multisynthase Complex Auxiliary Component P38 antibody
Anti-Protein Jtv-1 antibody
Anti-AIMP2 antibody
Anti-JTV1 antibody
Anti-PRO0992 antibody

Information sourced from Uniprot.org

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