| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AGFG1 |
| Gene ID: | 3267 |
| Uniprot ID: | AGFG1_HUMAN |
| Immunogen Region: | 1-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human AGFG1 (NP_004495.2). |
| Immunogen Sequence: | MAASAKRKQEEKHLKMLRDM TGLPHNRKCFDCDQRGPTYV NMTVGSFVCTSCSGSLRGLN PPHRVKSISMTTFTQQEIEF LQKHGNEVCKQIWLGLFDDR SSAIPDFRDPQKVKEFLQEK YEKKRWYVPPEQAKVVASVH ASISGSSASSTSSTPEVKPL KSLLGDSAPTLHLNKGTPSQ SPVVGRSQGQQQEKKQFDLL SDLGSDIFAAPAPQSTATAN FANFAHFNSHAAQNSANAD |
| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | O-glycosylated. |
| Function | Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. |
| Protein Name | Arf-Gap Domain And Fg Repeat-Containing Protein 1Hiv-1 Rev-Binding ProteinNucleoporin-Like Protein RipRev-Interacting ProteinRev/Rex Activation Domain-Binding Protein |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | NucleusCytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Arf-Gap Domain And Fg Repeat-Containing Protein 1 antibodyAnti-Hiv-1 Rev-Binding Protein antibodyAnti-Nucleoporin-Like Protein Rip antibodyAnti-Rev-Interacting Protein antibodyAnti-Rev/Rex Activation Domain-Binding Protein antibodyAnti-AGFG1 antibodyAnti-HRB antibodyAnti-RAB antibodyAnti-RIP antibody |
Information sourced from Uniprot.org
