• Human yolk sac tumor stained with anti-AFP polyclonal antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells..

Anti-AFP antibody [C3] (STJ180483)

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STJ180483

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-AFP is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: C3
Conjugation: Unconjugated
Isotype: IgG2a/Kappa
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: AFP
Gene ID: 174
Uniprot ID: FETA_HUMAN
Specificity: Positive control: Fetal liver or hepatocellular carcinoma
Immunogen: Alpha fetoprotein (AFP) purified from serum of a hepatoma patient
Tissue Specificity Plasma. Synthesized by the fetal liver and yolk sac.
Post Translational Modifications Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated.
Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Protein Name Alpha-Fetoprotein
Alpha-1-Fetoprotein
Alpha-Fetoglobulin
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Antibody Names Anti-Alpha-Fetoprotein antibody
Anti-Alpha-1-Fetoprotein antibody
Anti-Alpha-Fetoglobulin antibody
Anti-AFP antibody
Anti-HPAFP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance