Anti-AFM antibody (260-599) (STJ117448)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AFM (260-599) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AFM |
| Gene ID | 173 |
| Uniprot ID | AFAM_HUMAN |
| Immunogen Region | 260-599 |
| Immunogen Sequence | EDVSSNYDGCCEGDVVQCIR DTSKVMNHICSKQDSISSKI KECCEKKIPERGQCIINSNK DDRPKDLSLREGKFTDSENV CQERDADPDTFFAKFTFEYS RRHPDLSIPELLRIVQIYKD LLRNCCNTENPPGCYRYAED KFNETTEKSLKMVQQECKHF QNLGKDGLKYHYLIRLTKIA PQLSTEELVSLGEKMVTAFT TCCTLSEEFACVDNLADLVF GELCGVNENRTINPAVDHC |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 260-599 of human AFM (NP_001124.1). |
Additional Info
| Tissue Specificity | High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level). |
| Post Translational Modifications | N-glycosylated.more than 90% of the glycans are sialylated. |
| Function | Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier. |
| Protein Name | AfaminAlpha-AlbuminAlpha-Alb |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Afamin antibodyAnti-Alpha-Albumin antibodyAnti-Alpha-Alb antibodyAnti-AFM antibodyAnti-ALB2 antibodyAnti-ALBA antibody |
Information sourced from Uniprot.org