Anti-ADH4 antibody (1-380) (STJ27407)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADH4 (1-380) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADH4 |
| Gene ID | 127 |
| Uniprot ID | ADH4_HUMAN |
| Immunogen Region | 1-380 |
| Immunogen Sequence | MGTKGKVIKCKAAIAWEAGK PLCIEEVEVAPPKAHEVRIQ IIATSLCHTDATVIDSKFEG LAFPVIVGHEAAGIVESIGP GVTNVKPGDKVIPLYAPLCR KCKFCLSPLTNLCGKISNLK SPASDQQLMEDKTSRFTCKG KPVYHFFGTSTFSQYTVVSD INLAKIDDDANLERVCLLGC GFSTGYGAAINNAKVTPGST CAVFGLGGVGLSAVMGCKAA GASRIIGIDINSEKFVKAK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-380 of human ADH4 (NP_000661.2). |
Additional Info
| Function | Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh4Alcohol Dehydrogenase 2Alcohol Dehydrogenase 4Alcohol Dehydrogenase Class Ii Pi Chain |
| Database Links | Reactome: R-HSA-5365859Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-All-Trans-Retinol Dehydrogenase Nad(+ Adh4 antibodyAnti-Alcohol Dehydrogenase 2 antibodyAnti-Alcohol Dehydrogenase 4 antibodyAnti-Alcohol Dehydrogenase Class Ii Pi Chain antibodyAnti-ADH4 antibodyAnti-ADH2 antibody |
Information sourced from Uniprot.org