| Short Description : | Mouse monoclonal anti-Adenylosuccinate Lyase/ADSL (1-484aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/WB/ICC/IF/FACS |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | AT16C10 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | By protein-A affinity chromatography |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADSL |
| Gene ID: | 158 |
| Uniprot ID: | PUR8_HUMAN |
| Accession Number: | NP_000017 |
| Immunogen: | Recombinant human ADSL (1-484aa) purified from E. coli |
| Immunogen Region: | 1-484aa |
| Tissue Specificity | Ubiquitously expressed. Both isoforms are produced by all tissues. Isoform 2 is 10-fold less abundant than isoform 1. |
| Function | Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. |
| Protein Name | Adenylosuccinate LyaseAdslAslAdenylosuccinaseAsase |
| Database Links | Reactome: R-HSA-73817 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Adenylosuccinate Lyase antibodyAnti-Adsl antibodyAnti-Asl antibodyAnti-Adenylosuccinase antibodyAnti-Asase antibodyAnti-ADSL antibodyAnti-AMPS antibody |
Information sourced from Uniprot.org
