Host: |
Rabbit |
Applications: |
WB/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Beta-adducin (471-520 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ADD2 |
Gene ID: |
119 |
Uniprot ID: |
ADDB_HUMAN |
Immunogen Region: |
471-520 aa |
Specificity: |
Adducin Beta Polyclonal Antibody detects endogenous levels of Adducin Beta protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human ADD2 at the amino acid range 471-520 |
Post Translational Modifications | The N-terminus is blocked. |
Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit. |
Protein Name | Beta-AdducinErythrocyte Adducin Subunit Beta |
Database Links | Reactome: R-HSA-5223345 |
Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic Side |
Alternative Antibody Names | Anti-Beta-Adducin antibodyAnti-Erythrocyte Adducin Subunit Beta antibodyAnti-ADD2 antibodyAnti-ADDB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance