| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
ADCYAP1 |
| Gene ID: |
116 |
| Uniprot ID: |
PACA_HUMAN |
| Immunogen Region: |
100 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human ADCYAP1 (NP_001108.2). |
| Immunogen Sequence: |
SAGKHLQSLVARGVGGSLGG GAGDDAEPLSKRHSDGIFTD SYSRYRKQMAVKKYLAAVLG KRYKQRVKNKGRRIAYL |
| Function | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
| Protein Name | Pituitary Adenylate Cyclase-Activating PolypeptidePacap Cleaved Into - Pacap-Related PeptidePrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27Pacap-27Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38Pacap-38Pacap38 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Pituitary Adenylate Cyclase-Activating Polypeptide antibodyAnti-Pacap Cleaved Into - Pacap-Related Peptide antibodyAnti-Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 antibodyAnti-Pacap-27 antibodyAnti-Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 antibodyAnti-Pacap-38 antibodyAnti-Pacap38 antibodyAnti-ADCYAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
