Anti-ADCY2 antibody (490-570 aa) (STJ191656)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 490-570
General Information
| Short Description | Rabbit polyclonal anti-Adenylate cyclase type 2 (490-570 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADCY2 |
| Gene ID | 108 |
| Uniprot ID | ADCY2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 490-570 |
| Immunogen Region | 490-570 aa |
| Specificity | ADCY2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors. |
| Protein Name | Adenylate Cyclase Type 2Atp Pyrophosphate-Lyase 2Adenylate Cyclase Type IiAdenylyl Cyclase 2 |
| Database Links | Reactome: R-HSA-163359Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-170660Reactome: R-HSA-170670Reactome: R-HSA-418555Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-432040Reactome: R-HSA-5610787Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-9856530 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasm |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 2 antibodyAnti-Atp Pyrophosphate-Lyase 2 antibodyAnti-Adenylate Cyclase Type Ii antibodyAnti-Adenylyl Cyclase 2 antibodyAnti-ADCY2 antibodyAnti-KIAA1060 antibody |
Information sourced from Uniprot.org