| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADAM28 (199-440) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADAM28 |
| Gene ID: |
10863 |
| Uniprot ID: |
ADA28_HUMAN |
| Immunogen Region: |
199-440 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 199-440 of human ADAM28 (NP_055080.2). |
| Immunogen Sequence: |
VQEHEKYIEYYLVLDNGEFK RYNENQDEIRKRVFEMANYV NMLYKKLNTHVALVGMEIWT DKDKIKITPNASFTLENFSK WRGSVLSRRKRHDIAQLITA TELAGTTVGLAFMSTMCSPY SVGVVQDHSDNLLRVAGTMA HEMGHNFGMFHDDYSCKCPS TICVMDKALSFYIPTDFSSC SRLSYDKFFEDKLSNCLFNA PLPTDIISTPICGNQLVEMG EDCDCGTSEECTNICCDAK |
| Tissue Specificity | Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen. |
| Post Translational Modifications | Pro-domain removal and maturation may be, at least in part, autocatalytic. |
| Function | May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 28Adam 28Epididymal Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein IiEmdc IiMetalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein LMdc-L |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 28 antibodyAnti-Adam 28 antibodyAnti-Epididymal Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein Ii antibodyAnti-Emdc Ii antibodyAnti-Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein L antibodyAnti-Mdc-L antibodyAnti-ADAM28 antibodyAnti-ADAM23 antibodyAnti-MDCL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunohistochemistry analysis of SAV1 in paraffin-embedded Human colon using [KO Validated] SAV1 Rabbit polyclonal antibody (STJ11101465) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/90378/359716/STJ11101465_1__88301.1713124227.jpg?c=1 "Immunohistochemistry analysis of SAV1 in paraffin-embedded Human colon using [KO Validated] SAV1 Rabbit polyclonal antibody (STJ11101465) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.")
