| Tissue Specificity | Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen. |
| Post Translational Modifications | Pro-domain removal and maturation may be, at least in part, autocatalytic. |
| Function | May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 28Adam 28Epididymal Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein IiEmdc IiMetalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein LMdc-L |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 28 antibodyAnti-Adam 28 antibodyAnti-Epididymal Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein Ii antibodyAnti-Emdc Ii antibodyAnti-Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein L antibodyAnti-Mdc-L antibodyAnti-ADAM28 antibodyAnti-ADAM23 antibodyAnti-MDCL antibody |
Information sourced from Uniprot.org
