• Western blot analysis of extracts of various cell lines, using ACVR2A rabbit monoclonal antibody (STJ11102305) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
  • Western blot analysis of extracts of various cell lines, using ACVR2A rabbit monoclonal antibody (STJ11102305) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
  • Western blot analysis of extracts from wild type (WT) and ACVR2A knockout (KO) 293T cells, using [KO Validated] ACVR2A rabbit monoclonal antibody (STJ11102305) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-ACVR2A antibody (1-100) [S5MR] (STJ11102305)

SKU:
STJ11102305

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-ACVR2A (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S5MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACVR2A
Gene ID: 92
Uniprot ID: AVR2A_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ACVR2A (P27037).
Immunogen Sequence: MGAAAKLAFAVFLISCSSGA ILGRSETQECLFFNANWEKD RTNQTGVEPCYGDKDKRRHC FATWKNISGSIEIVKQGCWL DDINCYDRTDCVEKKDSPEV
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.
Protein Name Activin Receptor Type-2a
Activin Receptor Type Iia
Actr-Iia
Actriia
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-1433617
Reactome: R-HSA-1502540
Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Activin Receptor Type-2a antibody
Anti-Activin Receptor Type Iia antibody
Anti-Actr-Iia antibody
Anti-Actriia antibody
Anti-ACVR2A antibody
Anti-ACVR2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance