Anti-ACTRT1 antibody (241-291 aa) (STJ194507)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ACTT1 at the amino acid range 241-291
General Information
| Short Description | Rabbit polyclonal anti-Actin-related protein T1 (241-291 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACTRT1 |
| Gene ID | 139741 |
| Uniprot ID | ACTT1_HUMAN |
| Immunogen | Synthesized peptide derived from the human ACTT1 at the amino acid range 241-291 |
| Immunogen Region | 241-291 aa |
| Specificity | This antibody detects endogenous levels of ACTT1 at Human/Mouse/Rat |
Additional Info
| Function | Negatively regulates the Hedgehog (SHH) signaling. Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression. |
| Protein Name | Actin-Related Protein T1Arp-T1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonNucleusCytoplasmic VesicleSecretory VesicleAcrosomeBoth Detected In The Nucleus And CytoplasmLocalizes To The Nucleus Where It Binds Chromatin Upon Stimulation Of The Hedgehog Pathway |
| Alternative Antibody Names | Anti-Actin-Related Protein T1 antibodyAnti-Arp-T1 antibodyAnti-ACTRT1 antibodyAnti-ARPT1 antibodyAnti-HSD27 antibody |
Information sourced from Uniprot.org