Anti-ACTN2 antibody (C-Term) (STJ98460)

SKU:
STJ98460
$205.62 - $496.80
Processing The item has been added

Short Description :Mouse monoclonal anti-Alpha-actinin-2 (C-Term) for use in WB and IF in Human, Rat, Cow, Chicken, Dog, Pig and Zebrafish samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IF
Host:Mouse
Reactivity:Human/Rat/Cow/Chicken/Dog/Pig/Zebrafish
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Affinity purification
Dilution Range:WB 1:1000-1:2000
IF 1:100-1:500
Formulation:Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ACTN2
Gene ID:88
Uniprot ID:ACTN2_HUMAN
Immunogen:Purified recombinant human Actinin-Alpha 2 (C-terminus) protein fragments expressed in E.coli.
Immunogen Region:C-Term
Specificity:Actinin-Alpha 2 Monoclonal Antibody detects endogenous levels of Actinin-Alpha 2 protein.
Post Translational Modifications Ubiquitinated by FBXL22, leading to proteasomal degradation.
Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Protein Name Alpha-Actinin-2
Alpha-Actinin Skeletal Muscle Isoform 2
F-Actin Cross-Linking Protein
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-373753
Reactome: R-HSA-390522
Reactome: R-HSA-438066
Reactome: R-HSA-442982
Reactome: R-HSA-5673001
Reactome: R-HSA-9609736
Reactome: R-HSA-9617324
Reactome: R-HSA-9620244
Cellular Localisation Cytoplasm
Myofibril
Sarcomere
Z Line
Colocalizes With Myoz1 And Flnc At The Z-Lines Of Skeletal Muscle
Alternative Antibody Names Anti-Alpha-Actinin-2 antibody
Anti-Alpha-Actinin Skeletal Muscle Isoform 2 antibody
Anti-F-Actin Cross-Linking Protein antibody
Anti-ACTN2 antibody

Information sourced from Uniprot.org