Anti-ACSL3 antibody (652-672) (STJ113279)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ACSL3 (652-672) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACSL3 |
| Gene ID | 2181 |
| Uniprot ID | ACSL3_HUMAN |
| Immunogen Region | 652-672 |
| Immunogen Sequence | VIGFVVPNQKELTELARKKG LKGTWEELCNSCEMENEVLK VLSEAAISASLEKFEIPVKI RLSPEPWTPETGLVTDAFKL KRKELKTHYQADIERMYGRK |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 621-720 of human ACSL3 (NP_004448.2). |
Additional Info
| Function | Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity. |
| Protein Name | Fatty Acid Coa Ligase Acsl3Arachidonate--Coa LigaseLong-Chain Acyl-Coa Synthetase 3Lacs 3Long-Chain-Fatty-Acid--Coa Ligase 3Medium-Chain Acyl-Coa Ligase Acsl3 |
| Database Links | Reactome: R-HSA-434313Reactome: R-HSA-75876 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iii Membrane ProteinPeroxisome MembraneMicrosome MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Fatty Acid Coa Ligase Acsl3 antibodyAnti-Arachidonate--Coa Ligase antibodyAnti-Long-Chain Acyl-Coa Synthetase 3 antibodyAnti-Lacs 3 antibodyAnti-Long-Chain-Fatty-Acid--Coa Ligase 3 antibodyAnti-Medium-Chain Acyl-Coa Ligase Acsl3 antibodyAnti-ACSL3 antibodyAnti-ACS3 antibodyAnti-FACL3 antibodyAnti-LACS3 antibody |
Information sourced from Uniprot.org