Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity. |
Database Links | Reactome: R-HSA-110328 |
Cellular Localisation | NucleusChromosome |
Protein Name | Histone H2b Type 2-EH2b-Clustered Histone 21Histone H2b-Gl105Histone H2b.qH2b/Q |
Alternative Names | Anti-Histone H2b Type 2-E antibodyAnti-H2b-Clustered Histone 21 antibodyAnti-Histone H2b-Gl105 antibodyAnti-Histone H2b.q antibodyAnti-H2b/Q antibodyAnti-H2BC21 antibodyAnti-H2BFQ antibodyAnti-HIST2H2BE antibody |
Information sourced from uniprot.org