| Short Description : | Rabbit polyclonal anti-Acetyl-CoA acetyltransferase, mitochondrial (221-270 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACAT1 |
| Gene ID: | 38 |
| Uniprot ID: | THIL_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ACAT1 at the amino acid range 221-270 |
| Immunogen Region: | 221-270 aa |
| Specificity: | ACAT-1 Polyclonal Antibody detects endogenous levels of ACAT-1 protein. |
| Function | This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. |
| Protein Name | Acetyl-Coa Acetyltransferase - MitochondrialAcetoacetyl-Coa ThiolaseT2 |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-77108Reactome: R-HSA-77111Reactome: R-HSA-9837999Reactome: R-HSA-9854311Reactome: R-HSA-9915355 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Acetyl-Coa Acetyltransferase - Mitochondrial antibodyAnti-Acetoacetyl-Coa Thiolase antibodyAnti-T2 antibodyAnti-ACAT1 antibodyAnti-ACAT antibodyAnti-MAT antibody |
Information sourced from Uniprot.org
