Anti-ABO antibody (1-100) [S3MR] (STJ11102293)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal BGAT (1-100) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S3MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABO |
| Gene ID | 28 |
| Uniprot ID | BGAT_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MAEVLRTLAGKPKCHALRPM ILFLIMLVLVLFGYGVLSPR SLMPGSLERGFCMAVREPDH LQRVSLPRMVYPQPKVLTPC RKDVLVVTPWLAPIVWEGTF |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGAT (P16442). |
Additional Info
| Tissue Specificity | Expressed at high levels in testis. Also expressed in pancreas, uterus and lung and salivary gland. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Glycosyltransferase that catalyzes the transfer of carbohydrates to H antigen, forming the antigenic structures of the ABO blood group. |
| Protein Name | Histo-Blood Group Abo System TransferaseFucosylglycoprotein 3-Alpha-GalactosyltransferaseFucosylglycoprotein Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-N-AcetylgalactosaminyltransferaseGlycoprotein-Fucosylgalactoside Alpha-GalactosyltransferaseHisto-Blood Group A TransferaseA TransferaseHisto-Blood Group B TransferaseB TransferaseNagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form |
| Database Links | Reactome: R-HSA-9033807 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinSecretedMembrane-Bound Form In Trans Cisternae Of GolgiSecreted Into The Body Fluid |
| Alternative Antibody Names | Anti-Histo-Blood Group Abo System Transferase antibodyAnti-Fucosylglycoprotein 3-Alpha-Galactosyltransferase antibodyAnti-Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase antibodyAnti-Glycoprotein-Fucosylgalactoside Alpha-N-Acetylgalactosaminyltransferase antibodyAnti-Glycoprotein-Fucosylgalactoside Alpha-Galactosyltransferase antibodyAnti-Histo-Blood Group A Transferase antibodyAnti-A Transferase antibodyAnti-Histo-Blood Group B Transferase antibodyAnti-B Transferase antibodyAnti-Nagat Cleaved Into - Fucosylglycoprotein Alpha-N-Acetylgalactosaminyltransferase Soluble Form antibodyAnti-ABO antibody |
Information sourced from Uniprot.org