||WB, IHC-P, IF-P, ELISA
||Human, Mouse, Rat
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody anti-Lysophosphatidylserine Lipase Abhd12 (200-280 Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
||PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
||The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
||WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000
||Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
||ABHD12 polyclonal antibody (Lysophosphatidylserine Lipase Abhd12) binds to endogenous Lysophosphatidylserine Lipase Abhd12 at the amino acid region 200-280 Internal.
||The antiserum was produced against synthesized peptide derived from human ABHD12 at amino acid range 231-280
| Function || Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes. Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system. Also able to hydrolyze oxidized phosphatidylserine.oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways. Has a strong preference for very-long-chain lipid substrates.substrate specificity is likely due to improved catalysis and not improved substrate binding. |
| Protein Name || Lysophosphatidylserine Lipase Abhd122-Arachidonoylglycerol Hydrolase Abhd12Abhydrolase Domain-Containing Protein 12Habhd12Monoacylglycerol Lipase Abhd12Oxidized Phosphatidylserine Lipase Abhd12 |
| Database Links || Reactome: R-HSA-426048 |
| Cellular Localisation || Endoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names || Anti-Lysophosphatidylserine Lipase Abhd12 antibodyAnti-2-Arachidonoylglycerol Hydrolase Abhd12 antibodyAnti-Abhydrolase Domain-Containing Protein 12 antibodyAnti-Habhd12 antibodyAnti-Monoacylglycerol Lipase Abhd12 antibodyAnti-Oxidized Phosphatidylserine Lipase Abhd12 antibodyAnti-ABHD12 antibodyAnti-C20orf22 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance