• Western blot analysis of lysates from COLO cells, using ABCB10 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using ABCB10 Polyclonal Antibody

Anti-ABCB10 antibody (441-490 aa) (STJ91410)

SKU:
STJ91410

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ATP-binding cassette sub-family B member 10, mitochondrial (441-490 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCB10
Gene ID: 23456
Uniprot ID: ABCBA_HUMAN
Immunogen Region: 441-490 aa
Specificity: ABCB10 Polyclonal Antibody detects endogenous levels of ABCB10 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ABCB10 at the amino acid range 441-490
Function Catalyzes the export of an unknown physiological substrate from the mitochondrial matrix to the cytosol in an ATP-dependent manner. May also transport the heme analog Zn (II) mesoporphyrin (ZnMP) in an ATP dependent manner but can't export the heme precursor 5-aminolevulinic acid (ALA) from mitochondria. Plays a role in the early step of the heme biosynthetic process during insertion of iron into protoporphyrin IX (PPIX). In turn participates in hemoglobin synthesis and also protects against oxidative stress. In addition may be involved in mitochondrial unfolded protein response (UPRmt) signaling pathway, although ABCB10 probably does not participate in peptide export from mitochondria.
Protein Name Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial
Abc-Mitochondrial Erythroid Protein
Abc-Me Protein
Atp-Binding Cassette Transporter 10
Abc Transporter 10 Protein
Mitochondrial Atp-Binding Cassette 2
M-Abc2
Database Links Reactome: R-HSA-1369007
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Atp-Binding Cassette Sub-Family B Member 10 - Mitochondrial antibody
Anti-Abc-Mitochondrial Erythroid Protein antibody
Anti-Abc-Me Protein antibody
Anti-Atp-Binding Cassette Transporter 10 antibody
Anti-Abc Transporter 10 Protein antibody
Anti-Mitochondrial Atp-Binding Cassette 2 antibody
Anti-M-Abc2 antibody
Anti-ABCB10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance