Anti-AADAT antibody (Internal) (STJ73305)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-AADAT (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.IHC: In paraffin embedded Human Kidney shows mitochondrial staining in PCT. Recommended concentration, 2-4µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | AADAT |
| Gene ID | 51166 |
| Uniprot ID | AADAT_HUMAN |
| Accession Number | NP_057312.1; NP_872603.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | DRVIDFYSNQKD |
| Specificity | Both reported variants represent identical protein (NP_057312.1 and NP_872603.1). |
Additional Info
| Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
| Protein Name | Kynurenine/Alpha-Aminoadipate Aminotransferase - MitochondrialKat/Aadat2-Aminoadipate Aminotransferase2-Aminoadipate TransaminaseAlpha-Aminoadipate AminotransferaseAadatGlycine Transaminase AadatKynurenine Aminotransferase IiKynurenine--Glyoxylate Transaminase AadatKynurenine--Oxoglutarate Aminotransferase IiKynurenine--Oxoglutarate Transaminase 2Kynurenine--Oxoglutarate Transaminase IiMethionine--Glyoxylate Transaminase Aadat |
| Database Links | Reactome: R-HSA-71064Reactome: R-HSA-71240 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial antibodyAnti-Kat/Aadat antibodyAnti-2-Aminoadipate Aminotransferase antibodyAnti-2-Aminoadipate Transaminase antibodyAnti-Alpha-Aminoadipate Aminotransferase antibodyAnti-Aadat antibodyAnti-Glycine Transaminase Aadat antibodyAnti-Kynurenine Aminotransferase Ii antibodyAnti-Kynurenine--Glyoxylate Transaminase Aadat antibodyAnti-Kynurenine--Oxoglutarate Aminotransferase Ii antibodyAnti-Kynurenine--Oxoglutarate Transaminase 2 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Ii antibodyAnti-Methionine--Glyoxylate Transaminase Aadat antibodyAnti-AADAT antibodyAnti-KAT2 antibodyAnti-KYAT2 antibody |
Information sourced from Uniprot.org