• Western blot analysis of the lysates from HUVECcells using Collagen V Alpha 1 antibody.
  • Western blot analysis of COLO205 cells using A Cyclase V/VI Polyclonal Antibody
  • Western blot analysis of lysates from COLO205 cells, using ADCY5/6 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using A Cyclase V/VI Polyclonal Antibody

Anti-A Cyclase V/VI antibody (931-980 aa) (STJ91397)

SKU:
STJ91397

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Adenylate cyclase type 5 and Adenylate cyclase type 6 (931-980 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADCY6
ADCY5
Gene ID: 112
111
Uniprot ID: ADCY6_HUMAN
ADCY5_HUMAN
Immunogen Region: 931-980 aa
Specificity: A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ADCY5/6 at the amino acid range 931-980
Post Translational Modifications Phosphorylated by RAF1.
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion.
Protein Name Adenylate Cyclase Type 5
Atp Pyrophosphate-Lyase 5
Adenylate Cyclase Type V
Adenylyl Cyclase 5
Ac5
Database Links Reactome: R-HSA-163359
Reactome: R-HSA-163615
Reactome: R-HSA-164378
Reactome: R-HSA-170660
Reactome: R-HSA-170670
Reactome: R-HSA-381676
Reactome: R-HSA-400042
Reactome: R-HSA-418555
Reactome: R-HSA-418594
Reactome: R-HSA-418597
Reactome: R-HSA-432040
Reactome: R-HSA-5610787
Reactome: R-HSA-9660821
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Cilium
Alternative Antibody Names Anti-Adenylate Cyclase Type 5 antibody
Anti-Atp Pyrophosphate-Lyase 5 antibody
Anti-Adenylate Cyclase Type V antibody
Anti-Adenylyl Cyclase 5 antibody
Anti-Ac5 antibody
Anti-ADCY5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance