• Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Western blot analysis of K562 cells using 11 Beta-HSD1 Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000

Anti-1 beta-HSD1 antibody (STJ97255)

SKU:
STJ97255

Current Stock:
Host: Rabbit
Applications: WB, IHC-P, ELISA
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal anti-1 beta-HSD1 antibody is suitable for use in Western Blot, Immunohistochemistry and ELISA.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
IHC-p 1:100-1:300
ELISA 1:10000
Specificity: 11 beta-HSD1 polyclonal antibody detects endogenous levels of 11 beta-HSD1 protein.
Uniprot ID: DHI1_HUMAN
Gene ID: 3290
Gene Symbol: HSD11B1
Immunogen: Synthesized peptide derived from human 11beta-HSD1.
Immunogen Region: 1-50 aa, N-terminal
Post Translational Modifications Glycosylated.
Function Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol.
Protein Name Corticosteroid 11-Beta-Dehydrogenase Isozyme 1
11-Beta-Hydroxysteroid Dehydrogenase 1
11-Dh
11-Beta-Hsd1
Short Chain Dehydrogenase/Reductase Family 26c Member 1
Database Links Reactome: R-HSA-194002
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Corticosteroid 11-Beta-Dehydrogenase Isozyme 1 antibody
Anti-11-Beta-Hydroxysteroid Dehydrogenase 1 antibody
Anti-11-Dh antibody
Anti-11-Beta-Hsd1 antibody
Anti-Short Chain Dehydrogenase/Reductase Family 26c Member 1 antibody
Anti-HSD11B1 antibody
Anti-HSD11 antibody
Anti-HSD11L antibody
Anti-SDR26C1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance