||WB, IHC-P, ELISA
||Human, Mouse, Rat
||Rabbit polyclonal anti-1 beta-HSD1 antibody is suitable for use in Western Blot, Immunohistochemistry and ELISA.
||FOR RESEARCH USE ONLY (RUO).
||Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
||The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
||Store at-20°C, and avoid repeat freeze-thaw cycles.
||WB 1:500-1:2000IHC-p 1:100-1:300ELISA 1:10000
||11 beta-HSD1 polyclonal antibody detects endogenous levels of 11 beta-HSD1 protein.
||Synthesized peptide derived from human 11beta-HSD1.
||1-50 aa, N-terminal
| Post Translational Modifications || Glycosylated. |
| Function || Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol. |
| Protein Name || Corticosteroid 11-Beta-Dehydrogenase Isozyme 111-Beta-Hydroxysteroid Dehydrogenase 111-Dh11-Beta-Hsd1Short Chain Dehydrogenase/Reductase Family 26c Member 1 |
| Database Links || Reactome: R-HSA-194002 |
| Cellular Localisation || Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names || Anti-Corticosteroid 11-Beta-Dehydrogenase Isozyme 1 antibodyAnti-11-Beta-Hydroxysteroid Dehydrogenase 1 antibodyAnti-11-Dh antibodyAnti-11-Beta-Hsd1 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 26c Member 1 antibodyAnti-HSD11B1 antibodyAnti-HSD11 antibodyAnti-HSD11L antibodyAnti-SDR26C1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance