Adenylate Cyclase 10 Positive Control for STJ502868 is synthetically produced from the sequence and is suitable for use in western blot applications.
Applications
WB
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Dilution Range
WB: 1:500
Formulation
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction
Store at-20°C for long term storage. Avoid freeze-thaw cycles.
This is positive control is recommended for use in combination with Adenylate Cyclase 10 antibody STJ502868.
Additional Info
Tissue Specificity
Expressed in testis.
Function
Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation.
Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin
Alternative Peptide Names
Adenylate Cyclase Type 10 proteinGerm Cell Soluble Adenylyl Cyclase proteinSac proteinTesticular Soluble Adenylyl Cyclase proteinAdcy10 proteinSac proteinSacy protein
