SLC26A3 Blocking Peptide for STJ506232 peptide (STJ505911)

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STJ505911-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : SLC26A3 Blocking Peptide for STJ506232 is synthetically produced from the 520-570 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC26A3
Gene ID: 1811
Uniprot ID: S26A3_HUMAN
Immunogen Region: 520-570
Specificity: This blocking peptide is recommended for use in combination with SLC26A3 antibody, STJ506232
Immunogen: Synthetic peptide corresponding to amino acids within region 520-570 on human SCL26A3 protein.
Tissue Specificity Expressed in the colon. Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon.
Post Translational Modifications N-glycosylation is required for efficient cell surface expression, and protection from proteolytic degradation.
Function Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Peptide Name Chloride Anion Exchanger
Down-Regulated In Adenoma
Protein Dra
Solute Carrier Family 26 Member 3
Database Links Reactome: R-HSA-427601
Reactome: R-HSA-5619085
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Membrane
Cell Membrane
Localized In Sperm Membranes
Midpiece Of Sperm Tail
Colocalizes With Cftr At The Midpiece Of Sperm Tail
Alternative Peptide Names Chloride Anion Exchanger protein
Down-Regulated In Adenoma protein
Protein Dra protein
Solute Carrier Family 26 Member 3 protein
SLC26A3 protein
DRA protein

Information sourced from Uniprot.org

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