| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Skn1 Blocking Peptide for STJ506334 is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | POU2F3 |
| Gene ID: | 25833 |
| Uniprot ID: | PO2F3_HUMAN |
| Immunogen Region: | 150-200 |
| Specificity: | This blocking peptide is recommended for use in combination with Skn1 antibody, STJ506334 |
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
| Peptide Name | Pou Domain - Class 2 - Transcription Factor 3 Octamer-Binding Protein 11 Oct-11 Octamer-Binding Transcription Factor 11 Otf-11 Transcription Factor Pla-1 Transcription Factor Skn-1 |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Pou Domain - Class 2 - Transcription Factor 3 protein Octamer-Binding Protein 11 protein Oct-11 protein Octamer-Binding Transcription Factor 11 protein Otf-11 protein Transcription Factor Pla-1 protein Transcription Factor Skn-1 protein POU2F3 protein OTF11 protein PLA1 protein |
Information sourced from Uniprot.org