Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Skn1 Blocking Peptide for STJ506334 is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
POU2F3 |
Gene ID: |
25833 |
Uniprot ID: |
PO2F3_HUMAN |
Immunogen Region: |
150-200 |
Specificity: |
This blocking peptide is recommended for use in combination with Skn1 antibody, STJ506334 |
Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation. The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues. |
Peptide Name | Pou Domain - Class 2 - Transcription Factor 3Octamer-Binding Protein 11Oct-11Octamer-Binding Transcription Factor 11Otf-11Transcription Factor Pla-1Transcription Factor Skn-1 |
Cellular Localisation | Nucleus |
Alternative Peptide Names | Pou Domain - Class 2 - Transcription Factor 3 proteinOctamer-Binding Protein 11 proteinOct-11 proteinOctamer-Binding Transcription Factor 11 proteinOtf-11 proteinTranscription Factor Pla-1 proteinTranscription Factor Skn-1 proteinPOU2F3 proteinOTF11 proteinPLA1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance