| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation has no effect on catalytic activity. |
| Function | Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation. |
| Protein Name | Dna Topoisomerase 2-AlphaDna Topoisomerase Ii - Alpha Isozyme |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusNucleoplasmNucleolus |
| Alternative ELISA Names | Dna Topoisomerase 2-Alpha ELISA kitDna Topoisomerase Ii - Alpha Isozyme ELISA kitTop2a ELISA kitTop-2 ELISA kitTop2 ELISA kit |
| output | |
Information sourced from Uniprot.org