Rat TOP2 (Topoisomerase II) Sandwich ELISA Kit (STJE0012736)
SPECIFICATIONS
General Information
| Short Description | This TOP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.125ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Top2aUniprot ID=TOP2A_RAT" |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation has no effect on catalytic activity. |
| Function | Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation. |
| Protein Name | Dna Topoisomerase 2-AlphaDna Topoisomerase Ii - Alpha Isozyme |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusNucleoplasmNucleolus |
| Alternative ELISA Names | Dna Topoisomerase 2-Alpha ELISA kitDna Topoisomerase Ii - Alpha Isozyme ELISA kitTop2a ELISA kitTop-2 ELISA kitTop2 ELISA kit |
| output |
Information sourced from Uniprot.org