Rat PDE12 (Phosphodiesterase 12) Sandwich ELISA Kit (STJE0011336)

Rat PDE12 (Phosphodiesterase 12) Sandwich ELISA Kit (STJE0011336)

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STJE0011336
€541.80 - €755.40
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Short Description :This PDE12 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates or other biological fluids..
Applications:ELISA
Reactivity:Rat
Sensitivity:0.049ng/mL
Detection Limit:0.156-10ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:Pde12
Gene ID:306231
Uniprot ID:PDE12_RAT
Sample Type:serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells.
Protein Name 2' -5'-Phosphodiesterase 12
2'-Pde
2-Pde
Mitochondrial Deadenylase
Database Links Reactome: R-RNO-8983711
Cellular Localisation Mitochondrion Matrix
Alternative ELISA Names 2' -5'-Phosphodiesterase 12 ELISA kit
2'-Pde ELISA kit
2-Pde ELISA kit
Mitochondrial Deadenylase ELISA kit
Pde12 ELISA kit
output

Information sourced from Uniprot.org

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