Rat PDE12 (Phosphodiesterase 12) Sandwich ELISA Kit (STJE0011336)
SPECIFICATIONS
General Information
| Short Description | This PDE12 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.049ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Pde12 |
| Gene ID | 306231 |
| Uniprot ID | PDE12_RAT |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells. |
| Protein Name | 2' -5'-Phosphodiesterase 122'-Pde2-PdeMitochondrial Deadenylase |
| Database Links | Reactome: R-RNO-8983711 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative ELISA Names | 2' -5'-Phosphodiesterase 12 ELISA kit2'-Pde ELISA kit2-Pde ELISA kitMitochondrial Deadenylase ELISA kitPde12 ELISA kit |
| output |
Information sourced from Uniprot.org