| Short Description : | Recombinant-rat Erythropoietin/EPO-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Bioactivity |
| Host: | HEK293 Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤ 2 ng/ml. |
| Gene Symbol: | Epo |
| Gene ID: | 24335 |
| Uniprot ID: | EPO_RAT |
| Accession Number: | NP_058697.1 |
| Immunogen: | Rat |
| Immunogen Region: | 27-192aa |
| Immunogen Sequence: |
| Tissue Specificity | Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. |
| Function | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. |
| Protein Name | Erythropoietin |
| Database Links | Reactome: R-RNO-9027276Reactome: -RNO-9027284 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Erythropoietin proteinEpo protein |
Information sourced from Uniprot.org
