Tissue Specificity | Isoform PDE7A1: Found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. Isoform PDE7A2: Found abundantly in skeletal muscle and at low levels in heart. |
Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. |
Peptide Name | High Affinity 3' -5'-Cyclic-Amp Phosphodiesterase 7aHcp1Tm22Camp-Specific Phosphodiesterase 7a |
Database Links | Reactome: R-HSA-418555 |
Cellular Localisation | Isoform Pde7a1: CytoplasmCytosolPde7a1 (57 Kda) Is Located Mostly To Soluble Cellular FractionsIsoform Pde7a2: CytoplasmPde7a2 (50 Kda) Is Located To Particulate Cellular Fractions |
Alternative Peptide Names | High Affinity 3' -5'-Cyclic-Amp Phosphodiesterase 7a proteinHcp1 proteinTm22 proteinCamp-Specific Phosphodiesterase 7a proteinPDE7A protein |
Information sourced from Uniprot.org