PDE6 Beta Positive Control peptide (STJ504661)

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STJ504661-5
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Covered by St John's Laboratory Guarantee

Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : PDE6 Beta Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE6B
Gene ID: 5158
Uniprot ID: PDE6B_HUMAN
Function Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP. Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal.
Peptide Name Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta
Gmp-Pde Beta
Database Links Reactome: R-HSA-2485179
Reactome: R-HSA-2514859
Reactome: R-HSA-4086398
Cellular Localisation Membrane
Lipid-Anchor
Cell Projection
Cilium
Photoreceptor Outer Segment
Alternative Peptide Names Rod Cgmp-Specific 3' -5'-Cyclic Phosphodiesterase Subunit Beta protein
Gmp-Pde Beta protein
PDE6B protein
PDEB protein

Information sourced from Uniprot.org

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