| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Phospho-PDE11A Blocking Peptide is synthetically produced from the 100-200 sequence about the S163 and is suitable for use in western blot applications. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Pde11a |
| Gene ID: |
140928 |
| Uniprot ID: |
PDE11_RAT |
| Immunogen Region: |
100-200 |
| Immunogen: |
Synthetic peptide taken within amino acid region 100-200 on rat PDE11A protein. Phosphorylated Ser 163. |
| Tissue Specificity | Isoform 1 is expressed in brain, heart, kidney and liver, but not in prostate. Isoform 2 is specifically expressed in testis. Isoform 3 is expressed in various tissues including brain, lung, skeletal muscle, spleen, testis and prostate. |
| Function | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. |
| Peptide Name | Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11aCamp And Cgmp Phosphodiesterase 11a |
| Database Links | Reactome: R-RNO-418457Reactome: -RNO-418555 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Peptide Names | Dual 3' -5'-Cyclic-Amp And -Gmp Phosphodiesterase 11a proteinCamp And Cgmp Phosphodiesterase 11a proteinPde11a protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
