| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PARD6B Blocking Peptide for STJ506140 is synthetically produced from the 340-372 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
PARD6B |
| Gene ID: |
84612 |
| Uniprot ID: |
PAR6B_HUMAN |
| Immunogen Region: |
340-372 |
| Specificity: |
This blocking peptide is recommended for use in combination with PARD6B antibody, STJ506140 |
| Immunogen: |
Synthetic peptide corresponding to amino acids within region 340-372 on human Partitioning Defective 6 homolog beta. |
| Tissue Specificity | Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues. |
| Function | Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. |
| Peptide Name | Partitioning Defective 6 Homolog BetaPar-6 BetaPar-6b |
| Database Links | Reactome: R-HSA-420029Reactome: R-HSA-9013424 |
| Cellular Localisation | CytoplasmCell MembraneCell JunctionTight Junction |
| Alternative Peptide Names | Partitioning Defective 6 Homolog Beta proteinPar-6 Beta proteinPar-6b proteinPARD6B proteinPAR6B protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
