Nurr1 Blocking Peptide peptide (STJ504433)

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STJ504433-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Nurr1 Blocking Peptide is synthetically produced from the 566-591 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: NR4A2
Gene ID: 4929
Uniprot ID: NR4A2_HUMAN
Immunogen Region: 566-591
Immunogen: Synthetic peptide corresponding to amino acid region 566-591. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker. Sequence: CTQGLQRIFYLKLEDLVP
Tissue Specificity Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
Function Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
Peptide Name Nuclear Receptor Subfamily 4 Group A Member 2
Immediate-Early Response Protein Not
Orphan Nuclear Receptor Nurr1
Transcriptionally-Inducible Nuclear Receptor
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-4090294
Cellular Localisation Cytoplasm
Nucleus
Mostly Nuclear
Oxidative Stress Promotes Cytoplasmic Localization
Alternative Peptide Names Nuclear Receptor Subfamily 4 Group A Member 2 protein
Immediate-Early Response Protein Not protein
Orphan Nuclear Receptor Nurr1 protein
Transcriptionally-Inducible Nuclear Receptor protein
NR4A2 protein
NOT protein
NURR1 protein
TINUR protein

Information sourced from Uniprot.org

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