Nanobodies

Nanobodies

Nanobodies available from St John's Laboratory can be used in a range of laboratory applications including ELISA, flow cytometry, immunoprecipitation, western blot, immunofluorescence, and functional blocking assays. Our nanobodies target proteins across human, mouse, rat, and other species. All nanobodies in this range are monoclonal, alpaca-derived single-domain antibodies supplied with defined clone IDs. Find the right nanobody for your research.

Browse nanobodies validated for ELISA, FC, WB, IF, IP, and functional applications.

What are nanobodies?

Nanobodies (VHH antibodies) are the variable domains of the heavy-chain-only antibodies naturally found in camelids such as alpaca. Their compact single-domain structure, approximately 15 kDa in molecular weight, provides high thermal stability and solubility. This small size allows nanobodies to access epitopes within clefts, active sites, and conformationally restricted regions on target proteins that are inaccessible to conventional IgG antibodies.

Applications

ELISA
Flow Cytometry (FC/FCM)
Immunoprecipitation (IP)
Western Blot (WB)
Immunofluorescence (IF)
Functional Blocking and Neutralisation

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