| Tissue Specificity | In brain, strongly expressed in the globus pallidus/ventral pallidum complex, the substantia nigra pars reticulata and the entopeduncular nucleus (at protein level). Expressed in the external plexiform layer of the olfactory bulb (at protein level). May be weakly expressed in neocortex and striatum (at protein level). Highly expressed in brain.not detected in other tissues tested. Detected in the cingulate cortex, cortical plate and caudate putamen. In neocortex, specifically expressed in neurons of layers II/III and V. |
| Post Translational Modifications | Glycosylated. |
| Function | Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. |
| Protein Name | Lysosome-Associated Membrane Glycoprotein 5Brain And Dendritic Cell-Associated LampBrain-Associated Lamp-Like ProteinBad-LampLysosome-Associated Membrane Protein 5Lamp-5 |
| Database Links | |
| Cellular Localisation | Cytoplasmic Vesicle MembraneSingle-Pass Type I Membrane ProteinCell MembraneCell ProjectionDendriteCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneGrowth Cone MembraneEarly Endosome MembraneRecycling EndosomeEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneEndosome MembraneRecycles From The Vesicles Of The Endocytic Recycling Compartment (Erc) To The Plasma MembraneColocalizes With Unc93b1 In Large Endosomal Intracellular VesiclesAccumulates In The Endoplasmic Reticulum-Golgi Intermediate Compartment (Ergic) Before Its Disappearance Upon Activation By Cpg DinucleotidesAssociates With Cortical MembranesLocalizes Mostly In Cytoplasmic Vesicles Of Neuronal Cell BodyLocalizes To Synaptic Vesicles In A Subset Of Gabaergic Neurons |
| Alternative Protein Names | Lysosome-Associated Membrane Glycoprotein 5 proteinBrain And Dendritic Cell-Associated Lamp proteinBrain-Associated Lamp-Like Protein proteinBad-Lamp proteinLysosome-Associated Membrane Protein 5 proteinLamp-5 proteinLamp5 protein |
Information sourced from Uniprot.org
