Mouses LAMP5 protein (Recombinant) (C-hFc) (STJP020253)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Mouses LAMP5 Protein is expressed from Expi293 with hFc tag at the C-terminal.οΌIt contains Glu30-Glu235.
General Information
| Short Description | Recombinant-Mouses LAMP5-C-hFc protein was developed in hek293 cells using the region Glu30-Glu235. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | Lamp5 |
| Gene ID | 76161 |
| Uniprot ID | LAMP5_MOUSE |
| Immunogen | Recombinant Mouses LAMP5 Protein is expressed from Expi293 with hFc tag at the C-terminal.οΌIt contains Glu30-Glu235. |
| Immunogen Region | Glu30-Glu235 |
| Immunogen Sequence | EQEVENLSGLSTNPEKDIFV VRENGTTCLMAEFAAKFIVP YDVWASNYVDLITEQAEISL TRGAEVKGHCGHNESELEVF WVDHAYTLRMLFVKESHNTS KGPEATWNLNKVHFVYDSSE KTHFKAPVKVNKYIASSHHL SALVTPAGMSYECQAQQTIS LASSDPQKTVTMILSAVHIQ PFDIISDFVFSEEHKCPVDE QEQLEE |
Additional Info
| Tissue Specificity | In brain, strongly expressed in the globus pallidus/ventral pallidum complex, the substantia nigra pars reticulata and the entopeduncular nucleus (at protein level). Expressed in the external plexiform layer of the olfactory bulb (at protein level). May be weakly expressed in neocortex and striatum (at protein level). Highly expressed in brain.not detected in other tissues tested. Detected in the cingulate cortex, cortical plate and caudate putamen. In neocortex, specifically expressed in neurons of layers II/III and V. |
| Post Translational Modifications | Glycosylated. |
| Function | Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. |
| Protein Name | Lysosome-Associated Membrane Glycoprotein 5Brain And Dendritic Cell-Associated LampBrain-Associated Lamp-Like ProteinBad-LampLysosome-Associated Membrane Protein 5Lamp-5 |
| Database Links | |
| Cellular Localisation | Cytoplasmic Vesicle MembraneSingle-Pass Type I Membrane ProteinCell MembraneCell ProjectionDendriteCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneGrowth Cone MembraneEarly Endosome MembraneRecycling EndosomeEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneEndosome MembraneRecycles From The Vesicles Of The Endocytic Recycling Compartment (Erc) To The Plasma MembraneColocalizes With Unc93b1 In Large Endosomal Intracellular VesiclesAccumulates In The Endoplasmic Reticulum-Golgi Intermediate Compartment (Ergic) Before Its Disappearance Upon Activation By Cpg DinucleotidesAssociates With Cortical MembranesLocalizes Mostly In Cytoplasmic Vesicles Of Neuronal Cell BodyLocalizes To Synaptic Vesicles In A Subset Of Gabaergic Neurons |
| Alternative Protein Names | Lysosome-Associated Membrane Glycoprotein 5 proteinBrain And Dendritic Cell-Associated Lamp proteinBrain-Associated Lamp-Like Protein proteinBad-Lamp proteinLysosome-Associated Membrane Protein 5 proteinLamp-5 proteinLamp5 protein |
Information sourced from Uniprot.org