| Host: | Sheep/Sheep |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | This VWF antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: | Unconjugated/Biotin |
| Formulation: | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Purification: | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Determination Method: | Colormetric |
| Gene Symbol: | Vwf |
| Gene ID: | 22371 |
| Uniprot ID: | VWF_MOUSE |
| Immunogen: | Capture immunogen: Natural Mouse VWF protien.Detection Immunogen: Natural Mouse VWF protien. |
| Sample Type: | Serum, plasma and other biological fluids |
| Post Translational Modifications | All cysteine residues are involved in intrachain or interchain disulfide bonds. N- and O-glycosylated. |
| Function | Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
| Protein Name | Von Willebrand FactorVwf Cleaved Into - Von Willebrand Antigen 2Von Willebrand Antigen Ii |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-140837Reactome: -MMU-216083Reactome: -MMU-354192Reactome: -MMU-354194Reactome: -MMU-372708Reactome: -MMU-430116Reactome: -MMU-5674135Reactome: -MMU-75892Reactome: -MMU-76009 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalized To Storage Granules |
| Alternative Antibody Pair Names | Von Willebrand Factor antibody pairVwf Cleaved Into - Von Willebrand Antigen 2 antibody pairVon Willebrand Antigen Ii antibody pairVwf antibody pair |
Information sourced from Uniprot.org
